Buprenorphine

Buprenorphine is a semi-synthetic opioid that is used to treat opioid addiction in higher dosages (>2 mg), to control moderate acute pain in non-opioid-tolerant individuals in lower dosages (~200 μg), and to control moderate chronic pain in dosages ranging from 20-70 μg/hour. It is available in a variety of formulations: Subutex, Suboxone (Buprenorphine HCl and naloxone HCl; typically used for opioid addiction), Temgesic, Buprenex (solutions for injection often used for acute pain in primary-care settings), Norspan and Butrans (transdermal preparations used for chronic pain).

bup-chart.png

Bup